产品货号：
Z14943
中文名称：
Doublecortin/DCX抗体
英文名称：
Anti-Doublecortin/DCX Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Doublecortin/DCX Antibody |
| 指标别名 | DBCN;DC;DCX;doublecortin;Doublin;Lis X;Lissencephalin X;LISX;SCLH;XLIS |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | DCX |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human Doublecortin (74-100aa QSLRFHQNMELDFGHFDERDKTSRNMR). |
| 实际分子量 | 40KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Neuronal migration protein doublecortin,also known as doublin or lissencephalin-X,is a protein that in humans is encoded by the DCX gene.This gene encodes a member of the doublecortin family.The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains,which bind microtubules.In the developing cortex,cortical neurons must migrate over long distances to reach the site of their final differentiation.The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules.In addition,the encoded protein interacts with LIS1,the regulatory gamma subunit of platelet activating factor acetylhydrolase,and this interaction is important to proper microtubule function in the developing cortex.Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex,leading to epilepsy,mental retardation,subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males.Multiple transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | O43602 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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